[Cardiac Surgery Using Low-dose Heparin Combined with Nafamostat Mesilate in an Acute Hemorrhagic Stroke].

A 66-year-old man presented to our hospital complaining palpitation and fatigue. He was diagnosed with heart failure secondary to mitral regurgitation, left ventricular thrombus, and hemorrhagic stroke in right cerebral hemisphere. Cardiac surgery under cardiopulmonary bypass during acute phase of stroke or cerebral hemorrhage carries significant risk, including exacerbation of neurological complications due to intraoperative anticoagulation. To mitigate this risk, we employed a low-dose heparin regimen combined with nafamostat mesilate continuous infusion during surgery. The patient successfully underwent mitral valve plasty and left ventricular thrombectomy, with a favorable postoperative course and no new neurological deficits.

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PubMed
Published
2025-05-01
Primary Topic
Neurological Disorders and Treatments
Type
article
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article

[Cardiac Surgery Using Low-dose Heparin Combined with Nafamostat Mesilate in an Acute Hemorrhagic Stroke].

Tomonori Koga, Nobuhiro Mochizuki, Takashi Ueda, Norifumi Ohtani et al.
PubMed
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[Cardiac Surgery Using Low-dose Heparin Combined with Nafamostat Mesilate in an Acute Hemorrhagic Stroke].

Tomonori Koga, Nobuhiro Mochizuki, Takashi Ueda, Norifumi Ohtani, Shuhei Nishijima, Takashi Kawashima
article en

Abstract

A 66-year-old man presented to our hospital complaining palpitation and fatigue. He was diagnosed with heart failure secondary to mitral regurgitation, left ventricular thrombus, and hemorrhagic stroke in right cerebral hemisphere. Cardiac surgery under cardiopulmonary bypass during acute phase of stroke or cerebral hemorrhage carries significant risk, including exacerbation of neurological complications due to intraoperative anticoagulation. To mitigate this risk, we employed a low-dose heparin regimen combined with nafamostat mesilate continuous infusion during surgery. The patient successfully underwent mitral valve plasty and left ventricular thrombectomy, with a favorable postoperative course and no new neurological deficits.

PubMedVol. 78(5)
Sapporo Higashi Tokushukai Hospital (JP)
Openalex Percentile: Top 80%
Neurological Disorders and Treatments
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