Scientific Opinion on Benzophenone – 4 (CAS No. 4065-45-6, EC No. 223-772-2) used in cosmetics products – SCCS/1660/23
• BZP-4 is safe when used as UV filter up to a max. conc. of 5% in sunscreen, all leave-on products (tot. dermal aggregate). • BZP-4 is safe when used as UV filter up to a max. conc. of 5% in sunscreen, all rinse-off products (tot. dermal aggregate). • Same for lipstick, sunscreen propellant and pump spray (separately or in combination based on determ. aggregated exposure). • BZP-4 use as stabiliser when the product is exposed to light should remain within the conc. of. 5%, incl. UV-filter use. • This assessment did not cover the safety of Benzophenone-4 for the environment.
Authors
- Nicolas J. Cabaton (ORCID: https://orcid.org/0000-0001-6585-5569)
- Vera Rogiers (ORCID: https://orcid.org/0000-0003-0635-7740)
- Laurent Bodin (ORCID: https://orcid.org/0000-0002-6900-8874)
- Tamara Vanhaecke (ORCID: https://orcid.org/0000-0002-6685-7299)
- Natalie von Goetz (ORCID: https://orcid.org/0000-0001-5257-4573)
- A. Koutsodimou (ORCID: https://orcid.org/0000-0001-8114-3238)
- Éric Gaffet (ORCID: https://orcid.org/0000-0002-6451-3011)
- Janine Ezendam (ORCID: https://orcid.org/0000-0002-8677-1986)
- Pieter Jan Coenraads (ORCID: https://orcid.org/0000-0001-9458-7129)
- Henriqueta Louro (ORCID: https://orcid.org/0000-0001-9744-7332)
- Emilio Benfenati (ORCID: https://orcid.org/0000-0002-3976-5989)
- Tamara Van Haecke
- C. Galli (ORCID: https://orcid.org/0000-0003-0078-5488)
- M. Stępnik (ORCID: https://orcid.org/0000-0003-1586-2482)
- Emanuela Corsini (ORCID: https://orcid.org/0000-0002-6927-5956)
- Ulrike Bernauer
- S. Wijnhoven
- E. Panteri
- Christophe Rousselle
- Qasim Chaudhry
Institutions
- Centre National de la Recherche Scientifique (FR)
- University Medical Center Groningen (NL)
- Vrije Universiteit Brussel (BE)
- University of Chester (GB)
- University of Milan (IT)
- Mario Negri Institute for Pharmacological Research (IT)
- National and Kapodistrian University of Athens (GR)
- Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR)
- Federal Institute for Risk Assessment (DE)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- Toxicologie Alimentaire (FR)
- National Institute for Public Health and the Environment (NL)
- CEA Paris-Saclay (FR)
- Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail (FR)
- National Institute of Health Dr. Ricardo Jorge (PT)
- Institut Jean Lamour (FR)
- General Chemical State Laboratory
- Université de Lorraine (FR)
Publication Details
- Journal
- NAM journal.
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.namjnl.2025.100034
- Primary Topic
- Effects and risks of endocrine disrupting chemicals
- Type
- article
- Field-Weighted Citation Impact
- 0.00