Electroacupuncture at ST36 Treatment Suppresses the Microglial Pyroptosis Through Activating α7nAChR in a Rat Model of Asphyxial Cardiac Arrest
Our study revealed that EA-ST36 exerted neuroprotective effects with a potent anti-neuroinflammatory potential by suppressing microglial pyroptosis in a rat CA/CPR model, and these anti-neuroinflammatory properties are α7nAChR-dependent.
Authors
- Fang Zhao (ORCID: https://orcid.org/0000-0002-5774-2238)
- Zhaoyan Zhao (ORCID: https://orcid.org/0000-0002-0559-9548)
- Qin Yuan (ORCID: https://orcid.org/0000-0001-7838-4217)
- Shuang Wang (ORCID: https://orcid.org/0000-0002-1693-6888)
- Gangguo Ma
- Yongfei Liu (ORCID: https://orcid.org/0000-0003-0588-424X)
- Fei Guo
- Xude Sun (ORCID: https://orcid.org/0000-0002-8365-0644)
- Changjun Gao (ORCID: https://orcid.org/0000-0002-5860-6596)
- Xiao Xiao (ORCID: https://orcid.org/0009-0009-9618-4302)
Institutions
- Tang Du Hospital (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-07-01
- DOI
- https://doi.org/10.2147/jir.s525373
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Basic Research Program of Shaanxi Province