Gynecologic and obstetric complications in women with congenital fibrinogen disorders: insights from the Prospective Rare Bleeding Disorders Database
The high rate of obstetric complications in women with CFDs highlights the need for early diagnosis and the potential need for prophylaxis, as pregnancy may also pose risks in asymptomatic cases. Hotspot variants do not appear to increase the risk of obstetric complications.
Authors
- Alessandro Casini (ORCID: https://orcid.org/0000-0001-7910-933X)
- Rosanna Asselta (ORCID: https://orcid.org/0000-0001-5351-0619)
- Marguerite Neerman‐Arbez (ORCID: https://orcid.org/0000-0002-9351-4195)
- Marko Saracevic (ORCID: https://orcid.org/0000-0003-1484-2826)
- Michael Makris (ORCID: https://orcid.org/0000-0001-7622-7939)
- Amy D. Shapiro (ORCID: https://orcid.org/0000-0003-2821-7159)
- Adrianna Williamson
- Roberta Palla (ORCID: https://orcid.org/0000-0001-8837-2367)
- Danijela Miković
- Britta Laros‐van Gorkom
- Marzia Menegatti (ORCID: https://orcid.org/0000-0002-8527-7556)
- Mehran Karimi (ORCID: https://orcid.org/0000-0001-8555-1001)
- Simona Maria Siboni (ORCID: https://orcid.org/0000-0002-8456-7519)
- Flora Peyvandi (ORCID: https://orcid.org/0000-0001-7423-9864)
- Samin Mohsenian (ORCID: https://orcid.org/0000-0001-5004-4456)
- Andrea Cairo (ORCID: https://orcid.org/0000-0001-5011-9710)
- LK Jacobs
- Helen Pargantou
Institutions
- University of Geneva (CH)
- American University in Dubai (AE)
- Humanitas University (IT)
- Radboud University Nijmegen (NL)
- University of Milan (IT)
- Shiraz University of Medical Sciences (IR)
- Royal Hallamshire Hospital (GB)
- Dubai Hospital (AE)
- Radboud University Medical Center (NL)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- University Hospital of Geneva (CH)
- Children's Hospital Agia Sophia (GR)
- American College of Dubai (AE)
- Indiana Hemophilia and Thrombosis Center (US)
- IRCCS Humanitas Research Hospital (IT)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1016/j.rpth.2025.102960
- Citations
- 2
- Primary Topic
- Blood properties and coagulation
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- Università degli Studi di Milano
- Dipartimenti di Eccellenza
- European Commission
- Ministero della Salute
- Ministero dell’Istruzione, dell’Università e della Ricerca
- Ministero dell'Università e della Ricerca
- Executive Agency for Health and Consumers