Polyhydroxybutyrate nanoparticle improving the sensitivity of Pseudomonas aeruginosa to ceftriaxone and reducing the biofilm formation in vitro
The combination of PHB-NPs with CRO significantly enhances the antibacterial activity of CRO against P. aeruginosa. Moreover, sub-inhibitory concentrations (sub-MICs) of both PHB-NP-CRO and CRO alone effectively reduce the bacterium's ability to form biofilms and adhere to biotic surfaces.
Authors
- Jenan Atiyah Ghafil (ORCID: https://orcid.org/0000-0003-1461-302X)
- S. Sadiq
Institutions
- University of Baghdad (IQ)
Publication Details
- Journal
- Polymers in Medicine
- Published
- 2025-07-01
- DOI
- https://doi.org/10.17219/pim/203765
- Primary Topic
- Advanced Drug Delivery Systems
- Type
- article
- Field-Weighted Citation Impact
- 0.00