Norcholic Acid Promotes M1 Macrophage Polarization in Acute Pancreatitis by Activating the Wnt/β-Catenin Pathway
NorCA demonstrates dual clinical utility as both a novel diagnostic biomarker for AP and a promising molecular target for therapeutic intervention in severe AP and its concomitant systemic inflammatory response syndrome (SIRS).
Authors
- Jianshui Li (ORCID: https://orcid.org/0000-0002-3283-0792)
- Jun Yu
- Junning Liu (ORCID: https://orcid.org/0000-0003-0844-4071)
- Qian Dai (ORCID: https://orcid.org/0000-0002-9887-0156)
- Xingyu Liu (ORCID: https://orcid.org/0000-0002-6888-9649)
- Chuan Lan (ORCID: https://orcid.org/0000-0002-6101-222X)
- Qing Zhou
- Dawei Deng (ORCID: https://orcid.org/0000-0002-5602-4795)
- Linfeng Yang
Institutions
- North Sichuan Medical University (CN)
- Capital Medical University (CN)
- Affiliated Hospital of North Sichuan Medical College (CN)
- Nanchong Central Hospital (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2025-06-24
- DOI
- https://doi.org/10.31083/fbl39259
- Citations
- 1
- Primary Topic
- Pancreatitis Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- National Natural Science Foundation of China
- Office of Science