Mean Platelet Volume as a Predictor of Left Atrial Appendage Thrombus Resistance to Lysis in Patients With Atrial Fibrillation: Results of a 12-Month Follow-Up
This study confirmed that approximately 47% LAAT remains resistant to lysis 1 year after initial detection in patients with AF, regardless of the use of OACs. To our knowledge, this is the first time that platelet morphofunctional parameters, particularly MPV, have been identified as predictors of LAAT lysis resistance, and further research in this direction is needed.
Authors
- A. V. Mamarina (ORCID: https://orcid.org/0000-0002-8160-7060)
- N. Yu. Khorkova (ORCID: https://orcid.org/0000-0002-7083-3214)
- А. В. Белокурова (ORCID: https://orcid.org/0000-0002-6049-8985)
- Т. П. Гизатулина (ORCID: https://orcid.org/0000-0003-4472-8821)
- Е. А. Горбатенко (ORCID: https://orcid.org/0000-0003-3675-1503)
Institutions
- Russian Academy of Sciences (RU)
- Tomsk National Research Medical Center (RU)
Publication Details
- Journal
- Reviews in Cardiovascular Medicine
- Published
- 2025-06-27
- DOI
- https://doi.org/10.31083/rcm38943
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Education and Science of the Russian Federation