Aspergillus ochraceus: A Rare Cause of Paranasal Fungal Ball

Infection of paranasal sinuses is not uncommon. Fungal ball of the paranasal sinuses is a non-invasive form of paranasal sinus infection that has been documented to be more frequently caused by Aspergillus fumigatus than by other Aspergillus species and typically affects immunocompetent individuals more than those who are immunocompromised. Here, we report the first case of Aspergillus ochraceus (A. ochraceus) in an immunocompromised patient with post-trauma maxillary implant who presented with transient ischemic attack and incidental findings of fungal ball within the right maxillary sinus from the Computed Tomography (CT) scan. A. ochraceus is a species under the Aspergillus section Circumdati, a widely distributed fungus which is pathogenic to humans that can lead to various clinical implications. A. ochraceus was detected from paranasal tissue sent for culture. The laboratory culture findings were further supported by histopathological evidence of fungal hyphae and matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF) identification.

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Publication Details

Journal
IIUM Medical Journal Malaysia
Published
2025-07-01
DOI
https://doi.org/10.31436/imjm.v24i03.2662
Primary Topic
Infectious Diseases and Mycology
Type
article
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article

Aspergillus ochraceus: A Rare Cause of Paranasal Fungal Ball

Normi Ngah Mohamed, Sameh Awad, Nilesh Shah, Rukumani Devi Velayuthan et al.
IIUM Medical Journal Malaysia
Infectious Diseases and Mycology
article

Aspergillus ochraceus: A Rare Cause of Paranasal Fungal Ball

Normi Ngah Mohamed, Sameh Awad, Nilesh Shah, Rukumani Devi Velayuthan, Muhamad Ariff Sobani
article en

Abstract

Infection of paranasal sinuses is not uncommon. Fungal ball of the paranasal sinuses is a non-invasive form of paranasal sinus infection that has been documented to be more frequently caused by Aspergillus fumigatus than by other Aspergillus species and typically affects immunocompetent individuals more than those who are immunocompromised. Here, we report the first case of Aspergillus ochraceus (A. ochraceus) in an immunocompromised patient with post-trauma maxillary implant who presented with transient ischemic attack and incidental findings of fungal ball within the right maxillary sinus from the Computed Tomography (CT) scan. A. ochraceus is a species under the Aspergillus section Circumdati, a widely distributed fungus which is pathogenic to humans that can lead to various clinical implications. A. ochraceus was detected from paranasal tissue sent for culture. The laboratory culture findings were further supported by histopathological evidence of fungal hyphae and matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF) identification.

IIUM Medical Journal MalaysiaVol. 24(03)
University of Malaya (MY), Universiti Teknologi MARA (MY)
Openalex Percentile: Top 83%
Infectious Diseases and Mycology
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