Population pharmacokinetics of teicoplanin and dosage optimization in sepsis patients based on continuous renal replacement therapy
Teicoplanin therapy in sepsis patients undergoing CRRT necessitates individualized dosing. A PK model-based teicoplanin dosing regimen for sepsis patients with CRRT was proposed, whereas prospective clinical study is required to validate.
Authors
- Maojun Zhao
- Qian Sun (ORCID: https://orcid.org/0000-0001-8556-2464)
- Suwen Yang (ORCID: https://orcid.org/0000-0003-1963-7100)
- Xu Zhou
- Siyi Wang (ORCID: https://orcid.org/0009-0000-1483-5787)
- Hong Zhu (ORCID: https://orcid.org/0000-0002-2481-6739)
- Yanping Zheng
- Jiang Jian
Institutions
- IE University (ES)
- Guizhou Cancer Hospital (CN)
- Guizhou Provincial People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-07-01
- DOI
- https://doi.org/10.3389/fphar.2025.1621959
- Citations
- 2
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 2.79