T-cell repertoire correlates with cytokine imbalance in multiple sclerosis patients
Correlation of significantly altered T-cell repertoire with cytokine deviations in MS despite individual patient data variability indicates that future diagnostic strategies may need to address immune response patterns rather than individual protein targets.
Authors
- Rodolphe Poupardin (ORCID: https://orcid.org/0000-0001-5195-5155)
- Dirk Strunk (ORCID: https://orcid.org/0000-0003-1810-867X)
- Lisa Weidner (ORCID: https://orcid.org/0000-0001-9666-6517)
- Sandra Laner‐Plamberger (ORCID: https://orcid.org/0000-0002-1416-6023)
- Tanja Eichhorn (ORCID: https://orcid.org/0000-0003-4158-026X)
- Christof Jungbauer (ORCID: https://orcid.org/0000-0002-2482-7147)
- Paulus Stefan Rommer (ORCID: https://orcid.org/0000-0001-5209-6647)
- Viktoria Weber (ORCID: https://orcid.org/0000-0002-3963-9077)
- Tobias Zrzavy (ORCID: https://orcid.org/0000-0001-8909-1591)
- Georg Gratz
Institutions
- Universität für Weiterbildung Krems (AT)
- Paracelsus Medical University (AT)
- Austrian Red Cross (AT)
- Medical University of Vienna (AT)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-07-01
- DOI
- https://doi.org/10.3389/fimmu.2025.1604452
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Österreichische Forschungsförderungsgesellschaft
- HORIZON EUROPE European Research Council