Formulation of zein nanoparticles for augmenting the anti-inflammatory activity of dexketoprofen
These findings highlight the effectiveness of zein nanoparticles as a promising topical delivery system for Dexketoprofen. The optimized ZNs not only improved drug entrapment and stability but also provided superior anti-inflammatory efficacy and excellent skin tolerability, suggesting their potential for the treatment of inflammatory skin conditions.
Authors
- Mona H. Ibrahim (ORCID: https://orcid.org/0000-0002-8235-5715)
- Abdulla M.A. Mahmoud (ORCID: https://orcid.org/0000-0002-5930-4266)
- Moaz A. Eltabeeb (ORCID: https://orcid.org/0000-0001-5918-9870)
- Rofida Albash (ORCID: https://orcid.org/0000-0003-1775-264X)
- Eman F. Khaleel (ORCID: https://orcid.org/0000-0002-3499-1186)
- Ahmed T. Negmeldin (ORCID: https://orcid.org/0000-0003-3399-3435)
- Shaimaa Mosallam
- Manar Adel Abdelbari (ORCID: https://orcid.org/0000-0001-8273-2923)
- Wagdy M. Eldehna (ORCID: https://orcid.org/0000-0001-6996-4017)
- Mahmoud A. El Hassab (ORCID: https://orcid.org/0000-0002-6795-4816)
- Sherif S. Abdel Mageed (ORCID: https://orcid.org/0000-0003-0702-5035)
- S. H. Allam
- Zainab Ahmed
- Asmaa Elsayyad
- Maram A. El Hasab
Institutions
- Kafrelsheikh University (EG)
- Sinai University (EG)
- Cairo University (EG)
- Misr University for Science and Technology (EG)
- Mansoura University (EG)
- Gulf Medical University (AE)
- Al-Azhar University (EG)
- Tanta University (EG)
- Badr University in Cairo (EG)
- October 6 University (EG)
- King Salman International University
- Menoufia University (EG)
- King Khalid University (SA)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-07-01
- DOI
- https://doi.org/10.3389/fphar.2025.1560585
- Citations
- 8
- Primary Topic
- Advancements in Transdermal Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 6.33
Funders
- King Khalid University