Relaxin-2-secreting CAR-T cells exhibit enhanced efficacy in stromal-rich xenograft tumors
RLN2 may enhance the antitumor activity of CAR-T cells against solid tumors by promoting their infiltration into the tumor microenvironment.
Authors
- Hideaki Tahara (ORCID: https://orcid.org/0000-0002-1735-5372)
- Tomoya Ekawa (ORCID: https://orcid.org/0009-0005-4222-4736)
- Takashi Akazawa (ORCID: https://orcid.org/0000-0002-4155-9228)
- Hisataka Ogawa (ORCID: https://orcid.org/0000-0002-9317-5007)
- Yu Mizote (ORCID: https://orcid.org/0009-0006-9662-322X)
Institutions
- Osaka International Cancer Institute (JP)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-07-01
- DOI
- https://doi.org/10.3389/fimmu.2025.1506204
- Citations
- 3
- Primary Topic
- Pregnancy-related medical research
- Type
- article
- Field-Weighted Citation Impact
- 5.64
Funders
- Office of Intelligence and Counterintelligence
- Japan Society for the Promotion of Science