Evaluation of echocardiography monitoring in myotonic dystrophy type 1 patients
Based on the data of this large retrospective study, the occurrence of LV dysfunction in DM1 patients is rather low (7.4%) at baseline and increases with 6.5% at 72 months follow-up. There is a significant correlation between LV dysfunction and a widened QRS interval. Which could prompt earlier echocardiographic follow up in this patient group. Routine echocardiography is useful in DM1 however the interval of echocardiography could be shifted more towards 5 years in asymptomatic patients because of the slow progressive nature of the disease.
Authors
- Catharina G. Faber (ORCID: https://orcid.org/0000-0002-2467-067X)
- Frederik M.A. van den Heuvel (ORCID: https://orcid.org/0000-0001-9255-418X)
- Geertruida P. Bijvoet (ORCID: https://orcid.org/0000-0002-3475-0155)
- Kevin Vernooy (ORCID: https://orcid.org/0000-0002-8818-5964)
- Cheyenne E W Janssen
- Reinder Evertz (ORCID: https://orcid.org/0000-0002-7958-3098)
- Baziel G.M. van Engelen (ORCID: https://orcid.org/0000-0001-9867-9047)
- Robin Nijveldt (ORCID: https://orcid.org/0000-0003-1530-6363)
- D. Bovenkerk
- DW Den Uijl
- Isis B.T. Joosten (ORCID: https://orcid.org/0000-0002-1110-6172)
- Sander M. J. van Kuijk (ORCID: https://orcid.org/0000-0003-2796-729X)
Institutions
- Radboud University Nijmegen (NL)
- Maastricht University Medical Centre (NL)
- Radboud University Medical Center (NL)
- Maastricht University (NL)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2025-07-01
- DOI
- https://doi.org/10.3389/fcvm.2025.1574885
- Primary Topic
- Genetic Neurodegenerative Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00