Defining cervical spondylotic myelopathy surgical endotypes using comorbidity clustering: a Quality Outcomes Database cervical spondylotic myelopathy study
While patients with multimorbidity have worse baseline and postoperative PROs, they achieve similar functional and pain-related improvements following CSM surgery. Similarly, the comorbidity endotypes identified in this QOD cohort suggest that certain patterns of coexisting chronic conditions, such as overlapping diabetes and arthritis, are associated with different levels of disability but may not diminish the effectiveness of surgical intervention.
Authors
- Erica F. Bisson (ORCID: https://orcid.org/0000-0002-8583-8544)
- Paul Park (ORCID: https://orcid.org/0000-0002-0375-396X)
- Mohamad Bydon (ORCID: https://orcid.org/0000-0002-0543-396X)
- Cheerag D. Upadhyaya
- Oren N. Gottfried
- Andrew K. Chan (ORCID: https://orcid.org/0000-0002-9352-5281)
- Luis M. Tumialán (ORCID: https://orcid.org/0000-0003-1180-8438)
- Kevin T. Foley (ORCID: https://orcid.org/0000-0002-3111-3943)
- Eunice Yang (ORCID: https://orcid.org/0000-0002-9392-8910)
- Domagoj Coric (ORCID: https://orcid.org/0000-0001-8521-2691)
- Michael S. Virk (ORCID: https://orcid.org/0000-0002-8511-5602)
- Praveen V. Mummaneni
- Dean Chou (ORCID: https://orcid.org/0000-0003-0310-8263)
- John J. Knightly (ORCID: https://orcid.org/0000-0003-0917-9265)
- Eric A. Potts (ORCID: https://orcid.org/0000-0003-4349-2327)
- Jay D. Turner
- Kai-Ming Fu
- Michael Y. Wang (ORCID: https://orcid.org/0000-0002-6997-5995)
- Anthony L. Asher (ORCID: https://orcid.org/0000-0002-3596-3849)
- Juan S. Uribe (ORCID: https://orcid.org/0000-0002-2150-4211)
- Scott A. Meyer
- Regis W. Haid
- Chun‐Po Yen
- Christopher I. Shaffrey
- Harrison Howell
Institutions
- University of North Carolina at Chapel Hill (US)
- Barrow Neurological Institute (US)
- Mayo Clinic (US)
- Carolinas Healthcare System (US)
- University of Miami (US)
- Duke University (US)
- University of California, San Francisco (US)
- Cornell University (US)
- University of Utah (US)
- Carolina Neurosurgery and Spine Associates (US)
- Semmes Murphey Foundation (US)
- Indiana Spine Group (US)
- Neurological Surgery (US)
- University of Virginia (US)
- University of Tennessee at Knoxville (US)
- Columbia University (US)
Publication Details
- Journal
- Neurosurgical FOCUS
- Published
- 2025-07-01
- DOI
- https://doi.org/10.3171/2025.4.focus25207
- Primary Topic
- Cervical and Thoracic Myelopathy
- Type
- article
- Field-Weighted Citation Impact
- 0.00