PW-BALFC, a clinical dataset for detection and instance segmentation of bronchoalveolar lavage fluid cell

Bronchoalveolar lavage fluid (BALF) cytology provides an important basis for the diagnosis and treatment of lung diseases. Current cytological analysis of BALF relies on manual microscopic examination, which is time-consuming, laborious, and experience-dependent. Automated identification of BALF cytology helps increase the accuracy and speed of screening qualified samples and subsequent cytomorphology analysis. However, there is a lack of public clinical BALF cell datasets for the detection of different cell types and a lack of pixel-level annotations for cytomorphology analysis. In this work, high-resolution cell images from clinical bronchoalveolar lavage sample obtained at the Chinese PLA General Hospital from 2018-2024 were collected, and pixel-level high-quality instance annotations of seven cell types were labeled. In total, 2,105 clinical images were gathered, with 13,263 cells from seven distinct classes, via both contour fine labeling and bounding box labeling. The dataset was trained and tested by the YOLOv8 instance segmentation network. The results demonstrated that the dataset and model we provided are beneficial for the study of automated cell identification in BALF.

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Publication Details

Journal
Scientific Data
Published
2025-07-01
DOI
https://doi.org/10.1038/s41597-025-05452-4
Citations
2
Primary Topic
COVID-19 diagnosis using AI
Type
article
Field-Weighted Citation Impact
2.72
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article

PW-BALFC, a clinical dataset for detection and instance segmentation of bronchoalveolar lavage fluid cell

Tingwei Quan, Xu Teng, Sifan Li, Zhimei Duan et al.
2 citations
Scientific Data
COVID-19 diagnosis using AI
2.72
article

PW-BALFC, a clinical dataset for detection and instance segmentation of bronchoalveolar lavage fluid cell

Tingwei Quan, Xu Teng, Sifan Li, Zhimei Duan, Xiuli Wang, Lixin Xie, Qing Huang, Yinghan Shi, Fei Xie, Kaifei Wang, Ye Hu, Xin Shi, Hualin Mei
article en
2 citations

Abstract

Bronchoalveolar lavage fluid (BALF) cytology provides an important basis for the diagnosis and treatment of lung diseases. Current cytological analysis of BALF relies on manual microscopic examination, which is time-consuming, laborious, and experience-dependent. Automated identification of BALF cytology helps increase the accuracy and speed of screening qualified samples and subsequent cytomorphology analysis. However, there is a lack of public clinical BALF cell datasets for the detection of different cell types and a lack of pixel-level annotations for cytomorphology analysis. In this work, high-resolution cell images from clinical bronchoalveolar lavage sample obtained at the Chinese PLA General Hospital from 2018-2024 were collected, and pixel-level high-quality instance annotations of seven cell types were labeled. In total, 2,105 clinical images were gathered, with 13,263 cells from seven distinct classes, via both contour fine labeling and bounding box labeling. The dataset was trained and tested by the YOLOv8 instance segmentation network. The results demonstrated that the dataset and model we provided are beneficial for the study of automated cell identification in BALF.

Scientific DataVol. 12(1)
Nankai University (CN), Chinese PLA General Hospital (CN), Wuhan National Laboratory for Optoelectronics (CN), PLA Academy of Military Science (CN), Huazhong University of Science and Technology (CN), Wuhan Institute of Technology (CN)
Openalex Percentile: Top 10%
COVID-19 diagnosis using AI
2.72
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