Experts’ consensus on the management and treatment of individuals with X-linked hypophosphatemia across lifespan
Individuals with XLH often experience unmet needs throughout life; a multidisciplinary approach involving different specialists, is recommended. The new treatment with burosumab can provide an effective and safety therapeutic option in reducing the burden of the disease in both children and adults. Therefore, awareness about the XLH disease should be increased among stakeholders. The criteria and reimbursement policies of burosumab should be revised.
Authors
- M. Barale (ORCID: https://orcid.org/0000-0003-3441-2014)
- Giorgia Grassi (ORCID: https://orcid.org/0000-0002-7236-0713)
- Giampiero I. Baroncelli (ORCID: https://orcid.org/0000-0001-8465-5087)
- Natascia Di Iorgi (ORCID: https://orcid.org/0000-0002-4492-4585)
- Stefano Mora (ORCID: https://orcid.org/0000-0002-4781-6715)
- Pasquale Comberiati (ORCID: https://orcid.org/0000-0001-5209-9733)
- Stefano Stagi (ORCID: https://orcid.org/0000-0002-2259-4685)
- Laura Gianotti (ORCID: https://orcid.org/0000-0002-4857-2468)
- Barbara Ruggiero (ORCID: https://orcid.org/0000-0003-4442-7201)
- Sabrina Corbetta (ORCID: https://orcid.org/0000-0001-8140-3175)
- Danilo Fintini (ORCID: https://orcid.org/0000-0002-0103-7951)
- Giuseppe Vezzoli (ORCID: https://orcid.org/0000-0003-4481-5693)
- Francesco Emma (ORCID: https://orcid.org/0000-0002-0383-3468)
- Maria Luisa Brandi (ORCID: https://orcid.org/0000-0002-8741-0592)
- Filomena Cetani (ORCID: https://orcid.org/0000-0003-2558-9547)
- Valentina Camozzi (ORCID: https://orcid.org/0000-0002-1634-951X)
- Anna Grandone (ORCID: https://orcid.org/0000-0002-6343-4768)
- Andrea Palermo
- Sandro Giannini (ORCID: https://orcid.org/0000-0003-0796-9749)
- Rosaria Maddalena Ruggeri (ORCID: https://orcid.org/0000-0001-8899-684X)
- Pitea Marco
- Francesca Pigliaru (ORCID: https://orcid.org/0000-0002-3899-0391)
- Cristina Eller-Vainicher (ORCID: https://orcid.org/0000-0002-6805-5804)
- Vincenzo Rochira (ORCID: https://orcid.org/0000-0001-8169-0696)
- Elena Castellano (ORCID: https://orcid.org/0000-0001-6622-4267)
- Carrara Silvia
- Procopio Massimo (ORCID: https://orcid.org/0009-0000-0751-3798)
- Manuela Caruso Nicoletti (ORCID: https://orcid.org/0000-0002-6819-605X)
Institutions
- University of Pisa (IT)
- University of Messina (IT)
- University of Modena and Reggio Emilia (IT)
- University of Padua (IT)
- Vita-Salute San Raffaele University (IT)
- University of Cagliari (IT)
- University of Milan (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- Istituto Giannina Gaslini (IT)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- University of Catania (IT)
- Azienda Ospedaliero-Universitaria di Modena (IT)
- Meyer Children's Hospital (IT)
- Bambino Gesù Children's Hospital (IT)
- IRCCS Ospedale San Raffaele (IT)
- IRCCS Istituto Auxologico Italiano (IT)
- Associazione Italiana Vulvodinia Onlus (IT)
- Azienda Sanitaria Ospedaliera S.Croce e Carle Cuneo (IT)
- Azienda Ospedaliera Universitaria Policlinico "G. Martino" (IT)
- Campus Bio Medico University Hospital (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Azienda Ospedaliera Universitaria Pisana (IT)
- University of Florence (IT)
- University of Turin (IT)
- University of Genoa (IT)
Publication Details
- Journal
- Journal of Endocrinological Investigation
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1007/s40618-025-02611-7
- Citations
- 1
- Primary Topic
- Parathyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- Ministero della Salute
- European Rare Kidney Disease Reference Network