Platycodin D-mediated METTL16 downregulation promotes docetaxel treatment of prostate cancer by regulating ferroptosis
PD promotes PCa cell ferroptosis to enhance the therapeutic effect of DTX in PCa via the METTL16/m6A/NUPR1 axis. Our findings offer a novel strategy for improving the therapeutic efficacy of DTX in PCa.
Authors
- Xiaoxiao Sun (ORCID: https://orcid.org/0000-0002-9689-9385)
- Congming Xiang
- Yu‐Wei Wu (ORCID: https://orcid.org/0000-0002-5603-1194)
- Sheng Wu (ORCID: https://orcid.org/0000-0001-6630-3600)
- Yougan Chen (ORCID: https://orcid.org/0000-0001-8345-1226)
- Chengwen Sun
Institutions
- Jiangnan University (CN)
- Wuxi Fourth People's Hospital (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1186/s12885-025-14291-w
- Citations
- 2
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 1.87