BAIAP2 as a driver of tumor progression in urothelial bladder cancer
BAIAP2 was highly expressed in muscle-invasive and high-grade tumors and was associated with poor prognosis. It promoted metastasis and EMT through activation of cytoskeletal remodeling. These findings identified BAIAP2 as a promising biomarker and a potential therapeutic target for the aggressive UBC.
Authors
- Haide Qin (ORCID: https://orcid.org/0000-0002-8942-5755)
- Qiongqiong Lin
- Long Huang (ORCID: https://orcid.org/0000-0003-4925-5162)
- Yan Dong (ORCID: https://orcid.org/0009-0002-8144-7631)
- Honglian Ruan
Institutions
- Sun Yat-sen University (CN)
- Sixth Affiliated Hospital of Sun Yat-sen University (CN)
- Sun Yat-sen Memorial Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1186/s12885-025-14470-9
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Science and Technology Planning Project of Guangdong Province