Elevated KRAS protein level is associated with better survival in pancreatic cancer
The KRAS protein level correlated poorly with KRAS mRNA expression level and was not significantly associated with the type of mutation present. Interestingly, we found that patients with high KRAS protein level in their tumors had a better clinical outcome.
Authors
- Ole Christian Lingjærde (ORCID: https://orcid.org/0000-0003-3565-4912)
- Elin H. Kure (ORCID: https://orcid.org/0000-0002-5135-9916)
- Daniel Johan Hammer Nebdal
- Laxmi Silwal‐Pandit
- Julian Hamfjord (ORCID: https://orcid.org/0000-0002-8621-2009)
- Bjørn Steen Skålhegg (ORCID: https://orcid.org/0000-0002-3481-8084)
- Janne Lehtiö (ORCID: https://orcid.org/0000-0002-8100-9562)
- Stina Margrethe Stålberg
Institutions
- Oslo University Hospital (NO)
- University of Oslo (NO)
- Science for Life Laboratory (SE)
- University of South-Eastern Norway (NO)
- Karolinska Institutet (SE)
- Cancer Registry of Norway (NO)
- Cancer Genetics (United States) (US)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1186/s12885-025-14461-w
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universitetet i Sørøst-Norge