Genetically proxied therapeutic effect of antihypertensive drug use, breast cancer, and ovarian cancer’s risk: a drug-target Mendelian randomization study
Our study provides genetic evidence that CCBs increase the risk of OC, offering insight into the potential risks of pharmacological treatment with CCBs.
Authors
- Dongxu Jin
- Pengfei Liu (ORCID: https://orcid.org/0000-0001-7122-9126)
- Yunzhen Shi
- Chunxiao Dang (ORCID: https://orcid.org/0000-0001-8145-8774)
- Ruohan Wang (ORCID: https://orcid.org/0000-0002-5852-2026)
- Jinxing Liu
- Xiao Yu (ORCID: https://orcid.org/0009-0007-9796-9510)
- Qing Ma (ORCID: https://orcid.org/0009-0007-3505-688X)
- Xiaofeng Wang (ORCID: https://orcid.org/0009-0009-7771-4662)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1186/s12885-025-14350-2
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province