Acute appendicitis in patients suffering from Immunocompromising hematologic malignancies or chemotherapy-related leukopenia: a cohort study
Diagnosing acute appendicitis in patients with hematologic malignancies or chemotherapy-induced leukopenia poses significant challenges, as standard scoring systems prove unreliable. The presence of abdominal pain coupled with elevated C-reactive protein (CRP) levels should prompt a multidisciplinary evaluation and timely imaging. Surgical therapies, particularly laparoscopic approaches, appear safe and feasible in these patients. Ongoing research is essential to refine surgical strategies for the growing population of immunocompromised individuals.
Authors
- Oliver Kriege (ORCID: https://orcid.org/0000-0002-3274-7390)
- Ann‐Kathrin Lederer (ORCID: https://orcid.org/0000-0001-7984-9530)
- Hauke Lang (ORCID: https://orcid.org/0000-0001-9303-2148)
- Andrew Klein (ORCID: https://orcid.org/0000-0002-2651-8698)
- F. Bartsch (ORCID: https://orcid.org/0000-0001-6090-2530)
- Hannah Rasel
Institutions
- Johannes Gutenberg University Mainz (DE)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1186/s12885-025-14493-2
- Citations
- 1
- Primary Topic
- Appendicitis Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 2.25
Funders
- Universitätsmedizin der Johannes Gutenberg-Universität Mainz