Acute appendicitis in patients suffering from Immunocompromising hematologic malignancies or chemotherapy-related leukopenia: a cohort study

Diagnosing acute appendicitis in patients with hematologic malignancies or chemotherapy-induced leukopenia poses significant challenges, as standard scoring systems prove unreliable. The presence of abdominal pain coupled with elevated C-reactive protein (CRP) levels should prompt a multidisciplinary evaluation and timely imaging. Surgical therapies, particularly laparoscopic approaches, appear safe and feasible in these patients. Ongoing research is essential to refine surgical strategies for the growing population of immunocompromised individuals.

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Publication Details

Journal
BMC Cancer
Published
2025-07-01
DOI
https://doi.org/10.1186/s12885-025-14493-2
Citations
1
Primary Topic
Appendicitis Diagnosis and Management
Type
article
Field-Weighted Citation Impact
2.25

Funders

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article

Acute appendicitis in patients suffering from Immunocompromising hematologic malignancies or chemotherapy-related leukopenia: a cohort study

Oliver Kriege, Ann‐Kathrin Lederer, Hauke Lang, Andrew Klein et al.
1 citations
BMC Cancer
Appendicitis Diagnosis and Management
2.25
article

Acute appendicitis in patients suffering from Immunocompromising hematologic malignancies or chemotherapy-related leukopenia: a cohort study

Oliver Kriege, Ann‐Kathrin Lederer, Hauke Lang, Andrew Klein, F. Bartsch, Hannah Rasel
article en
1 citations

Abstract

Diagnosing acute appendicitis in patients with hematologic malignancies or chemotherapy-induced leukopenia poses significant challenges, as standard scoring systems prove unreliable. The presence of abdominal pain coupled with elevated C-reactive protein (CRP) levels should prompt a multidisciplinary evaluation and timely imaging. Surgical therapies, particularly laparoscopic approaches, appear safe and feasible in these patients. Ongoing research is essential to refine surgical strategies for the growing population of immunocompromised individuals.

BMC CancerVol. 25(1)
Johannes Gutenberg University Mainz (DE), University Medical Center of the Johannes Gutenberg University Mainz (DE)
Universitätsmedizin der Johannes Gutenberg-Universität Mainz
Good health and well-being
Openalex Percentile: Top 13%
Appendicitis Diagnosis and Management
2.25
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Acute appendicitis in patients suffering from Immunocompromising hematologic malignancies or chemotherapy-related leukopenia: a cohort study — Oliver Kriege, Ann‐Kathrin Lederer, et al. · BMC Cancer (2025) | TGRS Research Map | TGRS