Genetic mechanism of β-alanine metabolic pathway affecting colorectal cancer prognosis
This study indicates a pivotal genetic role for the β-alanine metabolic pathway, particularly rs2811182 in DPYD, in influencing CRC prognosis. These findings offer new perspectives for personalized treatment strategies and enhance our understanding of CRC pathogenesis.
Authors
- Sumeng Wang (ORCID: https://orcid.org/0000-0002-6546-0177)
- Lingxiang Liu (ORCID: https://orcid.org/0000-0001-8689-1788)
- Yi Jiao (ORCID: https://orcid.org/0000-0002-1413-5008)
- Yali Jiang (ORCID: https://orcid.org/0000-0003-4786-0465)
- Tingyu Zhao (ORCID: https://orcid.org/0009-0000-5673-8328)
- Liang Qi (ORCID: https://orcid.org/0000-0002-0235-7957)
- Siqi Ni
- Xiao Zhang (ORCID: https://orcid.org/0009-0002-9537-8120)
Institutions
- Jiangsu Province Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1186/s12876-025-04051-2
- Citations
- 1
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.94