An atypical presentation of infiltrative diffuse low-grade glioma in an adolescent: case report
While behavioral and psychiatric changes are common in brain tumor patients, they typically present alongside neurological symptoms which emphasizes the difficulty in diagnosing cases like this patient's. Low-grade malignancies should be part of the differential diagnosis in cases with progressive multifocal white matter lesions, despite the absence of the typical neurological focal signs.
Authors
- Ellen F. Macnamara (ORCID: https://orcid.org/0000-0002-9418-3287)
- Maria T. Acosta (ORCID: https://orcid.org/0000-0001-8914-7401)
- Sadhana Jackson (ORCID: https://orcid.org/0000-0001-6700-5621)
- John Yang (ORCID: https://orcid.org/0000-0002-7739-1009)
- Christopher H. Dampier (ORCID: https://orcid.org/0000-0003-3099-6462)
- David N. Korones
- John D. Heiss (ORCID: https://orcid.org/0000-0002-3890-0165)
- Zoe Wolfenson (ORCID: https://orcid.org/0009-0008-2207-5755)
- Kenneth Aldape (ORCID: https://orcid.org/0000-0001-5119-7550)
- Gilbert Vézina (ORCID: https://orcid.org/0000-0002-1999-336X)
- Connor Lewis (ORCID: https://orcid.org/0000-0002-8204-5848)
- Lynne A. Wolfe (ORCID: https://orcid.org/0000-0001-7628-5741)
- William A. Gahl (ORCID: https://orcid.org/0000-0002-2494-6752)
- Daniel Benavides
- Robert B. Stone
Institutions
- National Institutes of Health (US)
- National Human Genome Research Institute (US)
- National Institute of Neurological Disorders and Stroke (US)
- National Cancer Institute (US)
- University of Rochester (US)
Publication Details
- Journal
- BMC Neurology
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1186/s12883-025-04259-5
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health