Comparison of EfficientNet CNN models for multi-label chest X-ray disease diagnosis

The analysis of chest X-ray images, which are critical for the early diagnosis of many diseases, is a difficult and time-consuming process due to the multiple labeling requirements and similar looking pathologies. In traditional methods, expert physicians analyze high-resolution chest X-ray images to diagnose these diseases using observational methods, a process that can lead to human error and hence misdiagnosis or underdiagnosis. In this study, we aim to autonomously detect 14 different diseases that significantly affect human health and some cases even lead to death using chest X-ray images in a multi-class manner using deep learning techniques. Previous studies on chest X-ray images focus on a single disease or have low success rates, and the architectures presented in previous studies have high computational costs. The novelty of this work is that it presents a hybrid lightweight, fast and attention-based architecture with high classification performance. In this study, we used the ChestX-Ray14 dataset consisting of 112,104 labeled chest X-ray images of 14 disease classes. Eight deep learning architectures (EfficientNetB0-B7) and coordinate attention mechanism are used in the training and testing processes. The proposed EfficientNetB7 architecture achieved an average overall classification performance with an AUC value of 0.8265. The EfficientNet enhanced with coordinate attention architecture achieved a classification success with an AUC value of 0.8309. Moreover, when the proposed architecture and the individual disease classes are considered separately, higher classification success is achieved for eight of the 14 diseases in the dataset. Finally, the results of this study outperformed the classification performance of other similar studies in the literature in terms of AUC score. The results obtained in our study show that the proposed deep learning based lightweight and fast architecture can support radiologists in decision making in disease diagnosis. The use of autonomous disease diagnosis systems can support the protection of human health by preventing incomplete or erroneous diagnoses.

Authors

Institutions

Publication Details

Journal
PeerJ Computer Science
Published
2025-07-01
DOI
https://doi.org/10.7717/peerj-cs.2968
Citations
3
Primary Topic
COVID-19 diagnosis using AI
Type
article
Field-Weighted Citation Impact
4.08

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Comparison of EfficientNet CNN models for multi-label chest X-ray disease diagnosis

Buket Kaya, Murat Uçan, Reda Alhajj, Mehmet Kaya et al.
3 citations
PeerJ Computer Science
COVID-19 diagnosis using AI
4.08
article

Comparison of EfficientNet CNN models for multi-label chest X-ray disease diagnosis

Buket Kaya, Murat Uçan, Reda Alhajj, Mehmet Kaya, Osman Aygun
article en
3 citations

Abstract

The analysis of chest X-ray images, which are critical for the early diagnosis of many diseases, is a difficult and time-consuming process due to the multiple labeling requirements and similar looking pathologies. In traditional methods, expert physicians analyze high-resolution chest X-ray images to diagnose these diseases using observational methods, a process that can lead to human error and hence misdiagnosis or underdiagnosis. In this study, we aim to autonomously detect 14 different diseases that significantly affect human health and some cases even lead to death using chest X-ray images in a multi-class manner using deep learning techniques. Previous studies on chest X-ray images focus on a single disease or have low success rates, and the architectures presented in previous studies have high computational costs. The novelty of this work is that it presents a hybrid lightweight, fast and attention-based architecture with high classification performance. In this study, we used the ChestX-Ray14 dataset consisting of 112,104 labeled chest X-ray images of 14 disease classes. Eight deep learning architectures (EfficientNetB0-B7) and coordinate attention mechanism are used in the training and testing processes. The proposed EfficientNetB7 architecture achieved an average overall classification performance with an AUC value of 0.8265. The EfficientNet enhanced with coordinate attention architecture achieved a classification success with an AUC value of 0.8309. Moreover, when the proposed architecture and the individual disease classes are considered separately, higher classification success is achieved for eight of the 14 diseases in the dataset. Finally, the results of this study outperformed the classification performance of other similar studies in the literature in terms of AUC score. The results obtained in our study show that the proposed deep learning based lightweight and fast architecture can support radiologists in decision making in disease diagnosis. The use of autonomous disease diagnosis systems can support the protection of human health by preventing incomplete or erroneous diagnoses.

PeerJ Computer ScienceVol. 11
Dicle University (TR), Fırat University (TR), University of Calgary (CA)
Türkiye Bilimsel ve Teknolojik Araştırma Kurumu
Openalex Percentile: Top 6%
COVID-19 diagnosis using AI
4.08
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.