Leptomeningeal metastasis with sturge-weber syndrome-like gyriform calcification on imaging: a case report

This case presented diagnostic challenges due to extensive gyriform calcification and the "tram-track" sign, which occasionally resemble SWS. However, the patient's late onset, absence of prior calcification, and lack of facial hemangioma were atypical for SWS. Furthermore, non-dominant hemisphere calcification did not align with aphasia symptoms. This single-case observation demonstrates that LM may present with radiologically heterogeneous features, and emphasizes the necessity of histopathological confirmation for accurate diagnosis.

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Publication Details

Journal
BMC Neurology
Published
2025-07-01
DOI
https://doi.org/10.1186/s12883-025-04273-7
Primary Topic
Cancer Diagnosis and Treatment
Type
article
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article

Leptomeningeal metastasis with sturge-weber syndrome-like gyriform calcification on imaging: a case report

Chongbo Zhao, Z H Zhang, Zhiye Wang, Yue Zhang et al.
BMC Neurology
Cancer Diagnosis and Treatment
article

Leptomeningeal metastasis with sturge-weber syndrome-like gyriform calcification on imaging: a case report

Chongbo Zhao, Z H Zhang, Zhiye Wang, Yue Zhang, Junjun Liu, Jie Wei, Yang Liu
article en

Abstract

This case presented diagnostic challenges due to extensive gyriform calcification and the "tram-track" sign, which occasionally resemble SWS. However, the patient's late onset, absence of prior calcification, and lack of facial hemangioma were atypical for SWS. Furthermore, non-dominant hemisphere calcification did not align with aphasia symptoms. This single-case observation demonstrates that LM may present with radiologically heterogeneous features, and emphasizes the necessity of histopathological confirmation for accurate diagnosis.

BMC NeurologyVol. 25(1)
81th Hospital of PLA (CN), Huashan Hospital (CN)
Zero hunger
Openalex Percentile: Top 77%
Cancer Diagnosis and Treatment
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Leptomeningeal metastasis with sturge-weber syndrome-like gyriform calcification on imaging: a case report — Chongbo Zhao, Z H Zhang, et al. · BMC Neurology (2025) | TGRS Research Map | TGRS