Integrated genetic analysis of Alzheimer's disease and stroke subtypes: insights from LDSC, PLACO, and MR studies
Overall, our study revealed that AD shares genetic factors with multiple stroke subtypes, notably in brain tissues. MR analysis indicates AD is a risk factor for LAS and AS, but protective for CES.
Authors
- Ruohan Sun (ORCID: https://orcid.org/0000-0003-2687-776X)
- Xiangyu Wang (ORCID: https://orcid.org/0009-0000-3365-9010)
- Jinfeng Liu (ORCID: https://orcid.org/0000-0002-0343-8222)
- Joanna Guo
- Long Yu (ORCID: https://orcid.org/0000-0001-9041-0801)
- Jinzhao Jiang
Institutions
- Harbin Medical University (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- BMC Neurology
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1186/s12883-025-04278-2
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China