PDS5B positively regulates PTEN by binding to YTHDC1 to inhibit the malignant progression of endometrial carcinoma
PDS5B interacts with YTHDC1 and further regulates PTEN in endometrial cancer cells, thereby inhibiting the malignant development of the tumor. These findings indicate the potential part of PDS5B in the development of EC and provide new molecular targets for the treatment of EC.
Authors
- Yong Qian (ORCID: https://orcid.org/0000-0002-5186-0938)
- Hui Wang (ORCID: https://orcid.org/0000-0001-9220-0357)
- Qianyun Gao
- Jie Li (ORCID: https://orcid.org/0000-0002-0877-3257)
Institutions
- Soochow University (CN)
- Changzhou No.2 People's Hospital (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1007/s12672-025-03021-0
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Soochow University