Human placental mesenchymal stem cell-derived exosomes carrying hsa-let-7i-5p mitigate lung injury in a murine model of aspiration pneumonia
In a murine AP model, intra-tracheal administration of hpMSC-derived exosomes has ALI-mitigating effects, involving inflammation, oxidation, and apoptosis modulation, with hsa-let-7i-5p playing a pivotal mediating role.
Authors
- I‐Lin Tsai (ORCID: https://orcid.org/0000-0002-3951-5197)
- Hong-Phuc Vo-Nguyen (ORCID: https://orcid.org/0000-0002-9840-987X)
- Yen‐Hua Huang (ORCID: https://orcid.org/0000-0001-6347-3030)
- Chun‐Jen Huang (ORCID: https://orcid.org/0000-0002-1006-6762)
- Ching-Wei Chuang (ORCID: https://orcid.org/0000-0002-9605-9837)
- Chao-Yuan Chang (ORCID: https://orcid.org/0009-0007-5788-5208)
Institutions
- Can Tho University (VN)
- Wan Fang Hospital (TW)
- Taipei Medical University (TW)
Publication Details
- Journal
- Korean journal of anesthesiology
- Published
- 2025-07-01
- DOI
- https://doi.org/10.4097/kja.25037
- Citations
- 3
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 2.42