Effect of respiration-induced motion on a three-dimensional magnetic resonance imaging-based adaptive radiotherapy workflow in a 1.5T magnetic resonance linear accelerator

This study investigated the impact of respiratory-induced linear translational motion on ITV delineation and dosimetric accuracy in MR-guided RT. It was found that large respiratory amplitudes significantly compromised geometric and dosimetric precision, whereas frequency had minimal influence. The results emphasize the limitations of 3D Cartesian MRI due to motion-averaged artifacts and support the development of advanced imaging techniques for improving ITV delineation accuracy.