Malignant Melanoma Metastasis as a Cause of Small-Bowel Perforation

Objective: Symptomatic gastrointestinal metastases are observed in only about 2% of patients with malignant melanoma. We aim to present a case of jejunal perforation secondary to metastatic melanoma. Case: A 64-year-old patient with known metastatic malignant melanoma (involving the brain, liver, and lungs) presented to the emergency department with bowel obstruction symptoms. Abdominal computed tomography (CT) revealed jejunal perforation with significant wall thickening. The patient underwent segmental bowel resection and jejunojejunostomy and was discharged after a one-week hospital stay. Conclusions: Although small bowel metastases from malignant melanoma are relatively common, bowel perforation due to metastasis is extremely rare. Perforation should be considered in the differential diagnosis of acute abdomen in patients with malignant melanoma.