Changes in olfactory function and serum interleukin-6 levels in the acute phase of bipolar I disorder: a longitudinal study
The dynamic recovery of OS (impaired in acute phase, restored in euthymia) suggests its potential as a disease-activity biomarker in BD, while persistent OI deficits may reflect trait-related neurobiological features. However, their specificity and clinical utility require rigorous validation. There is a potential correlation between inflammatory activity and olfactory dysfunction in manic BD patients, but its causal relationship and specific mechanism need to be further verified.
Authors
- Chunyang Li (ORCID: https://orcid.org/0000-0001-7279-3669)
- Chao Chen (ORCID: https://orcid.org/0000-0002-5114-2282)
- Chunhong Yang (ORCID: https://orcid.org/0009-0003-3938-5382)
- Qiping Li
- Ziyuan Zhou
- Ao Zhao
Institutions
- The Fourth People's Hospital (CN)
Publication Details
- Journal
- BMC Psychiatry
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1186/s12888-025-07048-z
- Citations
- 1
- Primary Topic
- Olfactory and Sensory Function Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.46
Funders
- Southern Medical University