[68Ga]Ga-DOTATATE PET/CT in Well-differentiated Ovarian Neuroendocrine Tumor Associated With Mature Cystic Teratoma

A well-differentiated ovarian neuroendocrine tumour (NET) associated with a mature cystic teratoma is rarely reported in the literature: the histologic diagnosis of these tumours is challenging due to the absence of defined guidelines for such lesions. Molecular imaging using [ 68 Ga]Ga-DOTATATE PET/CT can play a pivotal role in evaluating somatostatin receptor (SSTR) expression for NET and assessing morphologic features for diagnosing teratoma, especially in patients of ovarian NET associated with mature cystic teratoma in single individual. In addition, [ 68 Ga]Ga-DOTATATE PET/CT offers advantages for implementing theranostic approaches in the treatment of these rare tumours, should this be contemplated.

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Journal
Clinical Nuclear Medicine
Published
2025-07-01
DOI
https://doi.org/10.1097/rlu.0000000000006017
Primary Topic
Neuroendocrine Tumor Research Advances
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article
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article

[68Ga]Ga-DOTATATE PET/CT in Well-differentiated Ovarian Neuroendocrine Tumor Associated With Mature Cystic Teratoma

Rahul V. Parghane, Sandip Kanti Basu, Rangat Bagasariya
Clinical Nuclear Medicine
Neuroendocrine Tumor Research Advances
article

[68Ga]Ga-DOTATATE PET/CT in Well-differentiated Ovarian Neuroendocrine Tumor Associated With Mature Cystic Teratoma

Rahul V. Parghane, Sandip Kanti Basu, Rangat Bagasariya
article en

Abstract

A well-differentiated ovarian neuroendocrine tumour (NET) associated with a mature cystic teratoma is rarely reported in the literature: the histologic diagnosis of these tumours is challenging due to the absence of defined guidelines for such lesions. Molecular imaging using [ 68 Ga]Ga-DOTATATE PET/CT can play a pivotal role in evaluating somatostatin receptor (SSTR) expression for NET and assessing morphologic features for diagnosing teratoma, especially in patients of ovarian NET associated with mature cystic teratoma in single individual. In addition, [ 68 Ga]Ga-DOTATATE PET/CT offers advantages for implementing theranostic approaches in the treatment of these rare tumours, should this be contemplated.

Clinical Nuclear MedicineVol. 51(3)
Bhabha Atomic Research Centre (IN), Homi Bhabha National Institute (IN), Tata Memorial Hospital (IN)
Good health and well-being
Openalex Percentile: Top 78%
Neuroendocrine Tumor Research Advances
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[68Ga]Ga-DOTATATE PET/CT in Well-differentiated Ovarian Neuroendocrine Tumor Associated With Mature Cystic Teratoma — Rahul V. Parghane, Sandip Kanti Basu, et al. · Clinical Nuclear Medicine (2025) | TGRS Research Map | TGRS