Mitochondrial Calcium Uniporter Regulates ITAM-Dependent Platelet Activation

Our data support a role for mitochondrial calcium flux in regulating ITAM-dependent platelet activation through the generation of mitochondrial ROS.

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Publication Details

Journal
Circulation Research
Published
2025-07-01
DOI
https://doi.org/10.1161/circresaha.125.326443
Citations
7
Primary Topic
Nitric Oxide and Endothelin Effects
Type
article
Field-Weighted Citation Impact
8.15
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article

Mitochondrial Calcium Uniporter Regulates ITAM-Dependent Platelet Activation

Dipayan Chaudhuri, Abigail Ajanel, David S. Paul, Frederik Denorme et al.
7 citations
Circulation Research
Nitric Oxide and Endothelin Effects
8.15
article

Mitochondrial Calcium Uniporter Regulates ITAM-Dependent Platelet Activation

Dipayan Chaudhuri, Abigail Ajanel, David S. Paul, Frederik Denorme, Irina Portier, Yasuhiro Kosaka, Shrutee Bhatt, Wolfgang Bergmeier, Izabella A. Andrianova, Robert A. Campbell, Abigail Ballard-Kordeliski, Mia Kowalczyk, Thomas C. Boone, Javier Pérez
article en
7 citations

Abstract

Our data support a role for mitochondrial calcium flux in regulating ITAM-dependent platelet activation through the generation of mitochondrial ROS.

Circulation ResearchVol. 137(4)
University of North Carolina at Chapel Hill (US), University of North Carolina Health Care (US), University of Utah (US), Anna Needs Neuroblastoma Answers (US)
Openalex Percentile: Top 2%
Nitric Oxide and Endothelin Effects
8.15
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