Skin melanoma cells produce diverse gelsolin (GSN) isoforms, which play non-redundant roles in cells’ proliferation and motility
Overall, we demonstrate that GSN isoforms are produced as a mixture in melanoma cells and are not redundant in their function. Therefore, to support the well-being of melanoma cells, a mixture of GSN isoforms must be produced.
Authors
- Iryna Kopernyk (ORCID: https://orcid.org/0000-0003-4621-7224)
- Antonina Joanna Mazur (ORCID: https://orcid.org/0000-0002-7561-9030)
- Paweł Karpiński (ORCID: https://orcid.org/0000-0003-3885-694X)
- Michał Majkowski (ORCID: https://orcid.org/0000-0002-9118-0005)
- Tomasz Trombik (ORCID: https://orcid.org/0000-0003-3643-8381)
- Aleksandra Makowiecka (ORCID: https://orcid.org/0000-0001-5030-684X)
- Anna Boguszewska‐Czubara
- Piotr Donizy (ORCID: https://orcid.org/0000-0002-8729-6216)
- Ewa Mazurkiewicz-Stanek
Institutions
- Medical University of Lublin (PL)
- University of Wrocław (PL)
- Wroclaw Medical University (PL)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1186/s12935-025-03876-x
- Primary Topic
- Cellular Mechanics and Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Narodowe Centrum Nauki
- Uniwersytet Medyczny im. Piastów Slaskich we Wroclawiu