Single-cell transcriptome of mouse hippocampus identifies neural precursor-like cells, and reveals IL15Rα knock out-mediated neuron remodeling
In summary, we demonstrate the precursor-like attributes of PLN and its potential as a regulatory fulcrum for adjusting brain's excitatory-inhibitory balance and robustness in IL15Rα-KO mice.
Authors
- Xuemei Huang (ORCID: https://orcid.org/0000-0002-5047-3522)
- Zuoli Sun (ORCID: https://orcid.org/0000-0003-1062-2009)
- Jian Yang
- Haixia Wang (ORCID: https://orcid.org/0000-0002-8165-7009)
- Yanting Luo (ORCID: https://orcid.org/0000-0003-0439-6164)
- Yi He (ORCID: https://orcid.org/0000-0002-0924-3530)
- Yadan Nie
Institutions
- Capital Medical University (CN)
- Beijing Anding Hospital (CN)
Publication Details
- Journal
- BMC Genomics
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1186/s12864-025-11785-6
- Citations
- 1
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.84
Funders
- National Natural Science Foundation of China