Steroid resistant bullous pemphigoid induced by pembrolizumab in a patient with metastatic lung adenocarcinoma: case report and review of the literature
This report adds to the growing body of evidence on IRAEs, particularly BP induced by ICIs, and suggests that methotrexate can be an effective treatment for steroid-resistant BP in the context of cancer immunotherapy. Further research is needed to better understand the mechanisms and optimal management strategies for ICI-induced BP.
Authors
- F. G. Kamar (ORCID: https://orcid.org/0000-0001-8470-5515)
- Elie S Bterrani
Institutions
- University of Balamand (LB)
- Centre François Baclesse (LU)
- American University of Beirut Medical Center (LB)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1007/s12672-025-02377-7
- Primary Topic
- Autoimmune Bullous Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00