Steroid resistant bullous pemphigoid induced by pembrolizumab in a patient with metastatic lung adenocarcinoma: case report and review of the literature

This report adds to the growing body of evidence on IRAEs, particularly BP induced by ICIs, and suggests that methotrexate can be an effective treatment for steroid-resistant BP in the context of cancer immunotherapy. Further research is needed to better understand the mechanisms and optimal management strategies for ICI-induced BP.

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Publication Details

Journal
Discover Oncology
Published
2025-07-01
DOI
https://doi.org/10.1007/s12672-025-02377-7
Primary Topic
Autoimmune Bullous Skin Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Steroid resistant bullous pemphigoid induced by pembrolizumab in a patient with metastatic lung adenocarcinoma: case report and review of the literature

F. G. Kamar, Elie S Bterrani
Discover Oncology
Autoimmune Bullous Skin Diseases
article

Steroid resistant bullous pemphigoid induced by pembrolizumab in a patient with metastatic lung adenocarcinoma: case report and review of the literature

F. G. Kamar, Elie S Bterrani
article en

Abstract

This report adds to the growing body of evidence on IRAEs, particularly BP induced by ICIs, and suggests that methotrexate can be an effective treatment for steroid-resistant BP in the context of cancer immunotherapy. Further research is needed to better understand the mechanisms and optimal management strategies for ICI-induced BP.

Discover OncologyVol. 16(1)
University of Balamand (LB), Centre François Baclesse (LU), American University of Beirut Medical Center (LB)
Good health and well-being
Openalex Percentile: Top 76%
Autoimmune Bullous Skin Diseases
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