Vertebral Metastasis With Syringomyelia Secondary to Breast Adenocarcinoma: A Case Report and Literature Review

Syringomyelia has several possible causes, commonly including Chiari malformation, spinal cord tumors and injuries, and damage caused by lesions around the spinal cord. A 34-year-old female was diagnosed with primary breast cancer and vertebral metastasis and was initiated on an extensive regimen of chemotherapy and radiotherapy. A few months later, she developed numbness and weakness in her lower limbs, and she was concluded to have syringomyelia with surrounding atrophic myelopathy along with vertebral metastasis. Patients developing neurological symptoms following radiotherapy or chemotherapy should be thoroughly evaluated, and further cases should be reported in the literature.

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Publication Details

Journal
Clinical Case Reports
Published
2025-07-01
DOI
https://doi.org/10.1002/ccr3.70580
Primary Topic
Spinal Dysraphism and Malformations
Type
article
Field-Weighted Citation Impact
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article

Vertebral Metastasis With Syringomyelia Secondary to Breast Adenocarcinoma: A Case Report and Literature Review

Hossam Tharwat Ali, Yara Ashour, Ahmed Reda Abdelhalim, Bishoy Adel Kamel Zakher
Clinical Case Reports
Spinal Dysraphism and Malformations
article

Vertebral Metastasis With Syringomyelia Secondary to Breast Adenocarcinoma: A Case Report and Literature Review

Hossam Tharwat Ali, Yara Ashour, Ahmed Reda Abdelhalim, Bishoy Adel Kamel Zakher
article en

Abstract

Syringomyelia has several possible causes, commonly including Chiari malformation, spinal cord tumors and injuries, and damage caused by lesions around the spinal cord. A 34-year-old female was diagnosed with primary breast cancer and vertebral metastasis and was initiated on an extensive regimen of chemotherapy and radiotherapy. A few months later, she developed numbness and weakness in her lower limbs, and she was concluded to have syringomyelia with surrounding atrophic myelopathy along with vertebral metastasis. Patients developing neurological symptoms following radiotherapy or chemotherapy should be thoroughly evaluated, and further cases should be reported in the literature.

Clinical Case ReportsVol. 13(7)
Ain Shams University (EG), South Valley University (EG), Al-Quds University (PS), University of Palestine (PS), Alexandria University (EG)
Good health and well-being
Openalex Percentile: Top 78%
Spinal Dysraphism and Malformations
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Vertebral Metastasis With Syringomyelia Secondary to Breast Adenocarcinoma: A Case Report and Literature Review — Hossam Tharwat Ali, Yara Ashour, et al. · Clinical Case Reports (2025) | TGRS Research Map | TGRS