Exploring the Cholinesterase Inhibitory Potential of Azines Bearing a 4,4-bisdimethylaminobenzophenone Scaffold: An Experimental and Computational Approach
These derivatives showed excellent AChE and BChE activities with favorable electronic properties and superior binding affinities, highlighting their potential as effective inhibitors as therapeutic agents.
Authors
- Momin Khan (ORCID: https://orcid.org/0000-0003-0936-5025)
- Abdullah F. Alasmari (ORCID: https://orcid.org/0000-0001-7569-4287)
- Ghulam Ahad
- Abid Ali (ORCID: https://orcid.org/0000-0001-6411-6625)
- Ahmed A. Elhenawy (ORCID: https://orcid.org/0000-0003-2893-0376)
- Fawaz F. Alasmari (ORCID: https://orcid.org/0000-0003-2382-5892)
- Imtiaz Ahmad (ORCID: https://orcid.org/0000-0003-2056-3540)
- Munir Ur Rehman (ORCID: https://orcid.org/0009-0002-1735-0114)
- Aftab Alam (ORCID: https://orcid.org/0000-0003-0475-2376)
- F Rahman
Institutions
- Harbin University of Science and Technology (CN)
- Universidade Federal de Pelotas (BR)
- Abdul Wali Khan University Mardan (PK)
- Al-Azhar University (EG)
- King Saud University (SA)
- Abbottabad University of Science and Technology (PK)
- University of Malakand (PK)
Publication Details
- Journal
- Medicinal Chemistry
- Published
- 2025-06-24
- DOI
- https://doi.org/10.2174/0115734064375363250620173232
- Primary Topic
- Cholinesterase and Neurodegenerative Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00