Pharmaceutical and Comparative Analysis of Shodhit Tamra, Dhatu Pishti (Tamra+Parad), and Tryambakeshwar Rasa (Mritloha) WSR to X-Ray Fluorescence Spectroscopy

IntroductionnbspRasashastranbspandnbspBhaishajya Kalpana a branch of Ayurveda specializes in preparing Ayurvedic medicines particularly of metallic and mineral origin.nbspBhasma derived from metals likenbspTamranbspcopper and Parad mercury undergoesnbspShodhananbsppurificationnbspMarananbspincineration and other processes to transform them into therapeutic agents. Modern techniques like x-ray fluorescence XRF spectroscopy ensure safety efficacy and standardization by analyzing the elemental composition of these formulations.Methods Ayurvedic methods fromnbspRasatarangininbspandnbspAyurved Prakashnbspwere employed for thenbspShodhananbspofnbspTamra Patra GandhaknbspandnbspParad. Key preparations includednbspTamra-Parad Dhatu PishtinbspandnbspTryambakeshwar Rasa Mritlohanbspby using trituration and heating techniques.nbspSiddhi Parikshanbspconfirmed compliance with traditional standards while XRF analysis assessed elemental composition.ResultsnbspThe pharmaceutical observations detailed the quantities of various substances processed and the respective losses incurred during the procedures. In the analytical assessment a comparison betweennbspShuddhanbspandnbspAshuddha Tamra Patranbsprevealed that while the copper content was consistent impurities such as iron and arsenic were notably reduced.nbspDhatu Pishtinbspwas found to contain 57.16 mercury as sulfates along with detectable amounts of copper and sulfur.nbspTryambakeshwar Rasanbspcontained 32.07 mercury and 35.54 sulfur as sulfates with other elements present only in trace quantities.ConclusionnbspXRF analysis highlights the compositional changes occurring during Ayurvedic pharmaceutical processes ensuring purity and therapeutic efficacy. These transformations align with traditional theories confirming the safety and standardization of the formulations.