The Baculovirus Expression System Expresses Chimeric RHDV VLPs as Bivalent Vaccine Candidates for Classic RHDV (GI.1) and RHDV2 (GI.2)
These data show that the chimeric RHDV VLP bivalent vaccine for immunized New Zealand rabbits can induce humoral immunity and cellular immunity in vivo, and the immunization effect of the high-dose group is similar to that of the current commercial vaccine.
Authors
- Derong Zhang (ORCID: https://orcid.org/0000-0002-2479-0591)
- Yan Wang (ORCID: https://orcid.org/0000-0003-3594-2658)
- Jialin Bai (ORCID: https://orcid.org/0000-0002-3505-1268)
- Yapeng Zhao (ORCID: https://orcid.org/0000-0002-4345-768X)
- Weidong Gao (ORCID: https://orcid.org/0000-0002-5323-9360)
- R. Bi (ORCID: https://orcid.org/0009-0004-5399-2565)
- Yiyang Fan (ORCID: https://orcid.org/0009-0004-3883-2213)
Institutions
- Minzu University of China (CN)
- State Ethnic Affairs Commission (CN)
Publication Details
- Journal
- Vaccines
- Published
- 2025-06-27
- DOI
- https://doi.org/10.3390/vaccines13070695
- Citations
- 1
- Primary Topic
- Viral Infectious Diseases and Gene Expression in Insects
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China