Bioorthogonal activation and mitochondrial targeting of a near-infrared-emitting iridium(<scp>iii</scp>) nitrone complex <i>via</i> cyclooctynylated phosphonium cations for enhanced cellular imaging and photodynamic therapy
In this work, we present the bioorthogonal activation and mitochondria targeting of a near-infrared-emitting iridium( iii ) nitrone complex via cyclooctynylated phosphonium cations for enhanced cellular imaging and photodynamic therapy.
Authors
- Nicholas J. Long (ORCID: https://orcid.org/0000-0002-8298-938X)
- Peter Kam‐Keung Leung (ORCID: https://orcid.org/0000-0002-6050-5276)
- Lawrence Cho‐Cheung Lee (ORCID: https://orcid.org/0000-0002-5046-0676)
- Edward R. H. Walter (ORCID: https://orcid.org/0000-0002-1396-3928)
- Kenneth Kam‐Wing Lo (ORCID: https://orcid.org/0000-0002-2470-5916)
Institutions
- City University of Hong Kong (HK)
- State Key Laboratory of Synthetic Chemistry (CN)
- Imperial College London (GB)
Publication Details
- Journal
- Inorganic Chemistry Frontiers
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5qi01139f
- Citations
- 2
- Primary Topic
- Click Chemistry and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- Innovation and Technology Commission
- Hong Kong Government