BCG Vaccination Potentially Modulates the Transcriptome of Infant CD4 T Cells in Addition to Age-Dependent Immune Ontogeny-Associated Changes
These findings are consistent with data reported in BCG vaccinated adults and contribute to the understanding of molecular changes in infant CD4 T cells that may explain the improved capacity of the infant immune system to respond to pathogens after BCG vaccination.
Authors
- Mina C. Hosseinipour (ORCID: https://orcid.org/0000-0003-2174-313X)
- Di Wu (ORCID: https://orcid.org/0000-0002-5622-7488)
- Gerald Tegha (ORCID: https://orcid.org/0000-0002-7744-5564)
- Emily E. Coates (ORCID: https://orcid.org/0000-0002-7561-351X)
- Portia Kamthunzi
- Eun-Young Kang
- Kristina De Paris (ORCID: https://orcid.org/0000-0001-5199-3004)
- Vidya Vijayan Karuvan Kandiyil
- Fei Zou (ORCID: https://orcid.org/0000-0002-6637-3593)
Institutions
- University of North Carolina at Chapel Hill (US)
- National Institute of Allergy and Infectious Diseases (US)
Publication Details
- Journal
- Vaccines
- Published
- 2025-06-29
- DOI
- https://doi.org/10.3390/vaccines13070706
- Primary Topic
- Immune responses and vaccinations
- Type
- article
- Field-Weighted Citation Impact
- 0.00