Lipid‐associated macrophages are more abundant in subcutaneous than visceral adipose tissue in patients with obesity
This study characterizes for the first time the macrophage biomarker signature in human VAT- and SAT-infiltrated CD11b<sup>+</sup> myeloid cells from individuals with severe obesity. Further studies are required to elucidate their potential role and specific function in the immunometabolism of individuals with obesity.
Authors
- Francesc Villarroya (ORCID: https://orcid.org/0000-0003-1266-9142)
- Rubén Cereijo (ORCID: https://orcid.org/0000-0002-1108-230X)
- Jordi Tarascó
- Lauro Sumoy (ORCID: https://orcid.org/0000-0003-0005-4618)
- Patricia Corrales (ORCID: https://orcid.org/0000-0002-9817-8389)
- Laura Herrero (ORCID: https://orcid.org/0000-0003-4244-4673)
- José M. Balibrea (ORCID: https://orcid.org/0000-0002-0764-7179)
- Ester Martínez-Martín (ORCID: https://orcid.org/0000-0003-4495-6912)
- David Sánchez‐Infantes (ORCID: https://orcid.org/0000-0001-6086-7501)
- Pau Moreno
- María Galán (ORCID: https://orcid.org/0000-0002-4758-8388)
- Sílvia Pellitero (ORCID: https://orcid.org/0000-0002-9510-7251)
- Marjorie Reyes‐Farias (ORCID: https://orcid.org/0000-0001-9179-7251)
- Andrea Soria‐Gondek (ORCID: https://orcid.org/0000-0002-7210-0073)
- Pablo Fernández‐García (ORCID: https://orcid.org/0000-0001-8018-5954)
- Lorena González (ORCID: https://orcid.org/0000-0002-5567-8922)
- Laia Gatell
- David Navarro‐Sanagustín (ORCID: https://orcid.org/0000-0003-4972-8193)
Institutions
- Universitat Autònoma de Barcelona (ES)
- Universidad Rey Juan Carlos (ES)
- Instituto de Salud Carlos III (ES)
- Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition (ES)
- Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (ES)
- Hospital Universitari Germans Trias i Pujol (ES)
- Universitat de Barcelona (ES)
Publication Details
- Journal
- Obesity
- Published
- 2025-06-29
- DOI
- https://doi.org/10.1002/oby.24323
- Citations
- 6
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 8.13
Funders
- Ministerio de Ciencia, Innovación y Universidades
- Generalitat de Catalunya
- Instituto de Salud Carlos III
- European Regional Development Fund
- Agencia Estatal de Investigación