Regulation of PKCi-mediated pluripotency and gene expression by polycomb complex 1 in mouse embryonic stem cells
These results indicate that PKCi activates both the canonical and non-canonical PRC1 pathways, finely regulates the expression of mES pluripotent and developmental genes, and helps maintain mES in a poised state between self-renewal and lineage commitment.
Authors
- Fangfang Wu (ORCID: https://orcid.org/0000-0002-1888-4516)
Institutions
- Nanjing Normal University (CN)
Publication Details
- Journal
- American Journal of Translational Research
- Published
- 2025-01-01
- DOI
- https://doi.org/10.62347/jvzi6615
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China