Breaking the biofilm- A persistent case of deep pyoderma in a Bullykutta dog

An eleven-month-old male Bullykutta dog was presented with a complaint of persistent skin infection in spite of treatment. The history revealed recurrence over four months, with the latest episode persisting for more than one month. Clinical examination showed hard, adherent crusts with erythema, alopecia, scaling and draining tracts of blood oozing lesions localized at the dorsum. Skin scrapings tested negative for mites, and no fleas or flea dirt’s were observed. Direct impression cytology revealed cocci, clusters of bacilli, and neutrophilic infiltration. Trichogram analysis identified trichorrhexis, with all hairs in the telogen phase. Culture confirmed Staphylococcus and Pseudomonas spp. ABST results showed sensitivity to ceftrioxone and resistance to other drugs. Based on history of draining tracts of blood oozing lesions and laboratory investigations the present was diagnosed as deep pyoderma with a mixed bacterial infection. Treatment began with cephalexin but was later switched to Sulphamethoxazole and trimethoprim due to recurrence. A 10-day regimen of Sulphamethoxazole and trimethoprim combined with omega fatty acid supplements and adjunctive topical therapy resulted in complete resolution and effectively preventing further recurrence of infection.