68Ga-DOTATATE PET/CT-Guided Surgical Resection for Complete Remission of Multifocal Insulinomas in a Father and Son With MEN1 Syndrome
A 49-year-old father and his 18-year-old son were diagnosed with multiple endocrine neoplasia syndrome type 1 (MEN-1). 68 Ga-DOTATATE PET/CT detected several insulinomas, and subsequent surgical intervention resulted in a complete cure. The father and son patients have both experienced episodes of hypoglycemia, in addition to having a parathyroid adenoma and a pituitary adenoma. Patients exhibit elevated levels of insulin, C-peptide, calcium, corrected calcium, parathyroid hormone (PTH), and prolactin.
Authors
- Hatice Uslu (ORCID: https://orcid.org/0000-0003-0456-261X)
- Mehmet Tarık Tatoğlu (ORCID: https://orcid.org/0000-0002-1680-4973)
Institutions
- Istanbul Medeniyet University (TR)
- National Patient Safety Foundation (US)
Publication Details
- Journal
- Clinical Nuclear Medicine
- Published
- 2025-06-30
- DOI
- https://doi.org/10.1097/rlu.0000000000005926
- Primary Topic
- Neuroendocrine Tumor Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 0.00