PD-L1 deficiency exacerbates colitis severity by remodeling gut microbiota in inflammatory bowel disease

PD-L1 deficiency aggravates colitis by driving pathogenic microbiota alterations and impairing microbial metabolic homeostasis, highlighting its dual regulatory roles in immune homeostasis and microbiome dynamics.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-06-30
DOI
https://doi.org/10.3389/fimmu.2025.1622744
Citations
1
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.81

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article

PD-L1 deficiency exacerbates colitis severity by remodeling gut microbiota in inflammatory bowel disease

Yixian Ma, Siqi Sheng, Jinshan Suo, Ling Chen
1 citations
Frontiers in Immunology
Gut microbiota and health
0.81
article

PD-L1 deficiency exacerbates colitis severity by remodeling gut microbiota in inflammatory bowel disease

Yixian Ma, Siqi Sheng, Jinshan Suo, Ling Chen
article en
1 citations

Abstract

PD-L1 deficiency aggravates colitis by driving pathogenic microbiota alterations and impairing microbial metabolic homeostasis, highlighting its dual regulatory roles in immune homeostasis and microbiome dynamics.

Frontiers in ImmunologyVol. 16
Shanghai University (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Eye & ENT Hospital of Fudan University (CN), Songjiang District Central Hospital (CN), The Affiliated Yongchuan Hospital of Chongqing Medical University (CN), Shandong Eye Hospital (CN), Chongqing Medical University (CN)
Shanghai Science and Technology Development Foundation, National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 26%
Gut microbiota and health
0.81
DOIOpen Access PDFOpenAlex
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PD-L1 deficiency exacerbates colitis severity by remodeling gut microbiota in inflammatory bowel disease — Yixian Ma, Siqi Sheng, et al. · Frontiers in Immunology (2025) | TGRS Research Map | TGRS