Evaluation of a novel chemiluminescent immunoassay for autoantibody detection in pemphigus and bullous pemphigoid
The novel CLIA, the first to quantify four major autoimmune blister disease autoantibodies (anti-Dsg1/anti-Dsg3/anti-BP180/anti-BP230) using a single sample tube, offers a simple and time-efficient test for diagnosing and screening pemphigus and BP. Its ability to assess disease severity and clinical relevance makes it a valuable tool for managing these conditions.
Authors
- Jing Tian (ORCID: https://orcid.org/0000-0001-8183-280X)
- Haizhou Zhou
- Qiuping Yu (ORCID: https://orcid.org/0000-0001-7476-866X)
- Jianwei Hao (ORCID: https://orcid.org/0000-0003-4819-314X)
- Hongwei Zhou (ORCID: https://orcid.org/0000-0002-7518-9464)
- Xia Liu (ORCID: https://orcid.org/0000-0002-8062-757X)
- Shuicheng Yan (ORCID: https://orcid.org/0000-0001-8906-3777)
- Na Zhang (ORCID: https://orcid.org/0000-0001-9534-0320)
- Ming Wang (ORCID: https://orcid.org/0000-0002-2836-1217)
- Xiaoqing Li (ORCID: https://orcid.org/0000-0002-7485-5592)
- Yanyu Zhang (ORCID: https://orcid.org/0009-0001-6623-2221)
- Liang Du (ORCID: https://orcid.org/0000-0003-1855-9139)
- Lili Hou (ORCID: https://orcid.org/0000-0002-3216-1365)
- Lixia Li
- Fangming Cheng
Institutions
- Harbin Medical University (CN)
- University of Cambridge (GB)
- Cambridge School (PT)
- Bridge University (SS)
- Lifetech Scientific (China) (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-06-30
- DOI
- https://doi.org/10.3389/fimmu.2025.1576635
- Citations
- 2
- Primary Topic
- Autoimmune Bullous Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.94
Funders
- Harbin Medical University
- National Natural Science Foundation of China
- Foundation for Innovative Research Groups of the National Natural Science Foundation of China