TrexAB, a novel tetracycline resistance determinant in Streptococcus dysgalactiae
We have characterized a novel operon causing low-grade resistance to tetracycline in SD. The MIC distribution of <i>trexAB</i>-positive isolates is intersected by the current EUCAST susceptibility breakpoint, and our findings are relevant for future revisions and determinations of adequate breakpoints for tetracycline in <i>S. dysgalactiae</i>.
Authors
- Steinar Skrede (ORCID: https://orcid.org/0000-0003-1615-4453)
- Zhian Salehian
- Marte Glambek
- Marita Torrissen Mårli (ORCID: https://orcid.org/0009-0001-1535-7032)
- Oddvar Oppegaard (ORCID: https://orcid.org/0000-0002-9665-218X)
- Morten Kjos (ORCID: https://orcid.org/0000-0003-4448-9082)
- Audun Sivertsen (ORCID: https://orcid.org/0000-0002-4283-6397)
- Bård Reiakvam Kittang
Institutions
- Haukeland University Hospital (NO)
- Deaconess Hospital (US)
- University of Bergen (NO)
- Norwegian University of Life Sciences (NO)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-06-30
- DOI
- https://doi.org/10.3389/fcimb.2025.1583926
- Primary Topic
- Streptococcal Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Haukeland Universitetssjukehus