Cytokine dysregulation in children with severe neurological impairment correlates with significant clinical outcomes
Children with SNI have persistent altered inflammatory responses. These alterations may contribute to tertiary neurological injury and impaired ability to respond to infection and may provide a target for immunomodulation.
Authors
- Denise McDonald (ORCID: https://orcid.org/0000-0002-6151-7404)
- Christopher Power (ORCID: https://orcid.org/0000-0002-5131-9711)
- Ashanty M. Melo (ORCID: https://orcid.org/0000-0001-6073-5429)
- Johana M. Isaza-Correa
- Lynne Kelly (ORCID: https://orcid.org/0000-0002-4782-1143)
- John Allen (ORCID: https://orcid.org/0000-0002-6205-3031)
- Eleanor J. Molloy (ORCID: https://orcid.org/0000-0001-6798-2158)
- Aoife Mahony
Institutions
- Trinity College Dublin (IE)
- Children's Health Ireland at Crumlin (IE)
- Coombe Women & Infants University Hospital (IE)
- St. James's Hospital (IE)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2025-06-30
- DOI
- https://doi.org/10.3389/fped.2025.1567221
- Primary Topic
- Neonatal and fetal brain pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Trinity College Dublin